Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease

In celiac disease (CD), an intolerance to dietary gluten/gliadin, antigenic gliadin peptides trigger an HLA-DQ2/DQ8-restricted adaptive Th1 immune response. Epithelial stress, induced by other non-antigenic gliadin peptides, is required for gliadin to become fully immunogenic. We found that cystic-f...

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Detalles Bibliográficos
Autores principales: Esposito, Speranza, Villella, Valeria Rachela, Ferrari, Eleonora, Monzani, Romina, Tosco, Antonella, Rossin, Federica, D’Eletto, Manuela, Castaldo, Alice, Luciani, Alessandro, Silano, Marco, Bona, Gianni, Marseglia, Gian Luigi, Romani, Luigina, Piacentini, Mauro, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503870/
https://www.ncbi.nlm.nih.gov/pubmed/30981209
http://dx.doi.org/10.18632/aging.101888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503870/
https://www.ncbi.nlm.nih.gov/pubmed/30981209
http://dx.doi.org/10.18632/aging.101888

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