Sex differences in the aging human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense

Aging is associated with increased inflammation and alterations in mitochondrial biogenesis, which promote the development of cardiovascular diseases. Emerging evidence suggests a role for sirtuins, which are NAD(+)-dependent deacetylases, in the regulation of cardiovascular inflammation and mitocho...

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Detalles Bibliográficos
Autores principales: Barcena de Arellano, Maria Luisa, Pozdniakova, Sofya, Kühl, Anja A., Baczko, Istvan, Ladilov, Yury, Regitz-Zagrosek, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503880/
https://www.ncbi.nlm.nih.gov/pubmed/30964749
http://dx.doi.org/10.18632/aging.101881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503880/
https://www.ncbi.nlm.nih.gov/pubmed/30964749
http://dx.doi.org/10.18632/aging.101881

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