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The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2(+) breast cancer cells

The chromodomain helicase DNA-binding 4 (CHD4), a member of the nucleosome remodeling and deacetylases (NuRD) complex, has been identified as an oncogene that modulates proliferation and migration of breast cancers (BC). ERBB2 is an oncogenic driver in 20–30% of BC in which its overexpression leads...

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Detalles Bibliográficos
Autores principales: D'Alesio, Carolina, Bellese, Grazia, Gagliani, Maria Cristina, Lechiara, Anastasia, Dameri, Martina, Grasselli, Elena, Lanfrancone, Luisa, Cortese, Katia, Castagnola, Patrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504000/
https://www.ncbi.nlm.nih.gov/pubmed/30967373
http://dx.doi.org/10.1242/bio.038323