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Dominant-negative inhibition of canonical Notch signaling in trophoblast cells does not disrupt placenta formation
Proper development and function of the mammalian placenta requires interactions between embryo-derived trophoblasts and uterine endothelial cells to form mosaic vessels that facilitate blood flow to a developing conceptus. Notch signaling utilizes a cell–cell contact dependent mechanism to drive cel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504009/ https://www.ncbi.nlm.nih.gov/pubmed/30971411 http://dx.doi.org/10.1242/bio.037721 |