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Dominant-negative inhibition of canonical Notch signaling in trophoblast cells does not disrupt placenta formation

Proper development and function of the mammalian placenta requires interactions between embryo-derived trophoblasts and uterine endothelial cells to form mosaic vessels that facilitate blood flow to a developing conceptus. Notch signaling utilizes a cell–cell contact dependent mechanism to drive cel...

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Detalles Bibliográficos
Autores principales: Shawber, Carrie J., Brown-Grant, Dex-Ann, Wu, Tracy, Kitajewski, Jan K., Douglas, Nataki C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504009/
https://www.ncbi.nlm.nih.gov/pubmed/30971411
http://dx.doi.org/10.1242/bio.037721