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Treatment of chronic HCV infection with DAAs in Rio de Janeiro/Brazil: SVR rates and baseline resistance analyses in NS5A and NS5B genes

The selection of viral strains with resistance-associated substitutions at hepatitis C virus (HCV) NS5A and NS5B genes is considered one of the limiting factors for achieving sustained virologic response (SVR) to combination of direct-acting antivirals daclatasvir (DCV) and sofosbuvir (SOF). Since 2...

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Detalles Bibliográficos
Autores principales: Costa, Vanessa D., Brandão-Mello, Carlos E., Nunes, Estevão P., dos Santos Silva, Pedro Guilherme Corôa, de Souza Rodrigues, Lia Laura Lewis Ximenez, Lampe, Elisabeth, do Amaral Mello, Francisco Campello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504041/
https://www.ncbi.nlm.nih.gov/pubmed/31063475
http://dx.doi.org/10.1371/journal.pone.0216327