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Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression

In the zebrafish, Fgf and Hh signalling assign anterior and posterior identity, respectively, to the poles of the developing ear. Mis-expression of fgf3 or inhibition of Hh signalling results in double-anterior ears, including ectopic expression of hmx3a. To understand how this double-anterior patte...

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Detalles Bibliográficos
Autores principales: Hartwell, Ryan D., England, Samantha J., Monk, Nicholas A. M., van Hateren, Nicholas J., Baxendale, Sarah, Marzo, Mar, Lewis, Katharine E., Whitfield, Tanya T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504108/
https://www.ncbi.nlm.nih.gov/pubmed/31022185
http://dx.doi.org/10.1371/journal.pgen.1008051