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A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease

PURPOSE: To determine whether DNase eye drops have the potential to reduce signs and symptoms of dry eye disease (DED). METHODS: A placebo-controlled, randomized clinical trial was performed to compare the safety and efficacy of DNase eye drops 0.1% four times a day for 8 weeks in patients with seve...

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Detalles Bibliográficos
Autores principales: Mun, Christine, Gulati, Shilpa, Tibrewal, Sapna, Chen, Yi-Fan, An, Seungwon, Surenkhuu, Bayasgalan, Raju, Ilangovan, Buwick, Morgan, Ahn, Anna, Kwon, Ji-Eun, Atassi, Nour, Pradeep, Anubhav, Rondelli, Damiano, Jain, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504128/
https://www.ncbi.nlm.nih.gov/pubmed/31110911
http://dx.doi.org/10.1167/tvst.8.3.10