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A bipartite iron-dependent transcriptional regulation of the tryptophan salvage pathway in Chlamydia trachomatis

During infection, pathogens are starved of essential nutrients such as iron and tryptophan by host immune effectors. Without conserved global stress response regulators, how the obligate intracellular bacterium Chlamydia trachomatis arrives at a physiologically similar ‘persistent’ state in response...

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Detalles Bibliográficos
Autores principales: Pokorzynski, Nick D, Brinkworth, Amanda J, Carabeo, Rey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504234/
https://www.ncbi.nlm.nih.gov/pubmed/30938288
http://dx.doi.org/10.7554/eLife.42295