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Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium

Enigma Homologue (ENH) is a component of the Z-disc, a structure that anchors actin filaments in the contractile unit of muscle, the sarcomere. Cardiac-specific ablation of ENH protein expression causes contractile dysfunction that ultimately culminates in dilated cardiomyopathy. However, whether EN...

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Detalles Bibliográficos
Autores principales: Gregorich, Zachery R., Patel, Jitandrakumar R., Cai, Wenxuan, Lin, Ziqing, Heurer, Rachel, Fitzsimons, Daniel P., Moss, Richard L., Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504290/
https://www.ncbi.nlm.nih.gov/pubmed/30642915
http://dx.doi.org/10.1085/jgp.201812214