Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity

Various mutations in the structural proteins nebulin and titin that are present in human disease are known to affect the contractility of striated muscle. Loss of nebulin is associated with reduced actin filament length and impairment of myosin binding to actin, whereas titin is thought to regulate...

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Detalles Bibliográficos
Autores principales: Mijailovich, Srboljub M., Stojanovic, Boban, Nedic, Djordje, Svicevic, Marina, Geeves, Michael A., Irving, Thomas C., Granzier, Henk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504291/
https://www.ncbi.nlm.nih.gov/pubmed/30948421
http://dx.doi.org/10.1085/jgp.201812165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504291/
https://www.ncbi.nlm.nih.gov/pubmed/30948421
http://dx.doi.org/10.1085/jgp.201812165

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