Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were re...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer - Medknow
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504724/ https://www.ncbi.nlm.nih.gov/pubmed/31114647 http://dx.doi.org/10.4103/jovr.jovr_92_18 |
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author | Jamali, Hossein Gholampour, Ahmad Reza |
author_facet | Jamali, Hossein Gholampour, Ahmad Reza |
author_sort | Jamali, Hossein |
collection | PubMed |
description | PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were reviewed. RESULTS: A total of 1149 eyes of 956 patients underwent corneal transplantation. The most common indication was infectious corneal ulcers (n = 296, 25.8%), followed by keratoconus (n = 243, 21.1%), bullous keratopathy (n = 219, 19.1%), failed grafts (n = 117, 10.2%), non-herpetic corneal scars (n = 113, 9.8%), corneal stromal dystrophies (n = 33, 2.9%), pellucid marginal degeneration (n = 31, 2.7%), and trauma (n = 26, 2.3%); other indications included thin descemetocele, post-herpetic corneal scar, endothelial corneal dystrophies, anterior segment dysgenesis, corneal ectasia after laser in situ keratomileusis, and corneal fibrosis. Corneal transplantation techniques included penetrating keratoplasty (PKP, n = 789, 68.7%), deep anterior lamellar keratoplasty (DALK, n = 187, 16.3%), Descemet's stripping automated endothelial keratoplasty (n = 171, 14.9%), and keratolimbal allograft (n = 2, 0.1%) in descending order. In children (aged ≤18 years), the most common indication was keratoconus (n = 32, 41.6%), and the most common technique was PKP (n = 50, 64.9%). In patients aged 19-27 years, the most common indication was keratoconus (n = 89, 64.5%), and the most common technique was PKP (n = 75, 54.4%). CONCLUSION: Infectious corneal ulcer was the most common indication, and PKP was the most prevalent technique in patients undergoing corneal transplantation. DALK was an emerging alternative surgical treatment in patients with corneal disorders in which corneal endothelium is spared. |
format | Online Article Text |
id | pubmed-6504724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65047242019-05-21 Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center Jamali, Hossein Gholampour, Ahmad Reza J Ophthalmic Vis Res Original Article PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were reviewed. RESULTS: A total of 1149 eyes of 956 patients underwent corneal transplantation. The most common indication was infectious corneal ulcers (n = 296, 25.8%), followed by keratoconus (n = 243, 21.1%), bullous keratopathy (n = 219, 19.1%), failed grafts (n = 117, 10.2%), non-herpetic corneal scars (n = 113, 9.8%), corneal stromal dystrophies (n = 33, 2.9%), pellucid marginal degeneration (n = 31, 2.7%), and trauma (n = 26, 2.3%); other indications included thin descemetocele, post-herpetic corneal scar, endothelial corneal dystrophies, anterior segment dysgenesis, corneal ectasia after laser in situ keratomileusis, and corneal fibrosis. Corneal transplantation techniques included penetrating keratoplasty (PKP, n = 789, 68.7%), deep anterior lamellar keratoplasty (DALK, n = 187, 16.3%), Descemet's stripping automated endothelial keratoplasty (n = 171, 14.9%), and keratolimbal allograft (n = 2, 0.1%) in descending order. In children (aged ≤18 years), the most common indication was keratoconus (n = 32, 41.6%), and the most common technique was PKP (n = 50, 64.9%). In patients aged 19-27 years, the most common indication was keratoconus (n = 89, 64.5%), and the most common technique was PKP (n = 75, 54.4%). CONCLUSION: Infectious corneal ulcer was the most common indication, and PKP was the most prevalent technique in patients undergoing corneal transplantation. DALK was an emerging alternative surgical treatment in patients with corneal disorders in which corneal endothelium is spared. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6504724/ /pubmed/31114647 http://dx.doi.org/10.4103/jovr.jovr_92_18 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Jamali, Hossein Gholampour, Ahmad Reza Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title | Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title_full | Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title_fullStr | Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title_full_unstemmed | Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title_short | Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center |
title_sort | indications and surgical techniques for corneal transplantation at a tertiary referral center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504724/ https://www.ncbi.nlm.nih.gov/pubmed/31114647 http://dx.doi.org/10.4103/jovr.jovr_92_18 |
work_keys_str_mv | AT jamalihossein indicationsandsurgicaltechniquesforcornealtransplantationatatertiaryreferralcenter AT gholampourahmadreza indicationsandsurgicaltechniquesforcornealtransplantationatatertiaryreferralcenter |