Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center

PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were re...

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Autores principales: Jamali, Hossein, Gholampour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504724/
https://www.ncbi.nlm.nih.gov/pubmed/31114647
http://dx.doi.org/10.4103/jovr.jovr_92_18
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author Jamali, Hossein
Gholampour, Ahmad Reza
author_facet Jamali, Hossein
Gholampour, Ahmad Reza
author_sort Jamali, Hossein
collection PubMed
description PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were reviewed. RESULTS: A total of 1149 eyes of 956 patients underwent corneal transplantation. The most common indication was infectious corneal ulcers (n = 296, 25.8%), followed by keratoconus (n = 243, 21.1%), bullous keratopathy (n = 219, 19.1%), failed grafts (n = 117, 10.2%), non-herpetic corneal scars (n = 113, 9.8%), corneal stromal dystrophies (n = 33, 2.9%), pellucid marginal degeneration (n = 31, 2.7%), and trauma (n = 26, 2.3%); other indications included thin descemetocele, post-herpetic corneal scar, endothelial corneal dystrophies, anterior segment dysgenesis, corneal ectasia after laser in situ keratomileusis, and corneal fibrosis. Corneal transplantation techniques included penetrating keratoplasty (PKP, n = 789, 68.7%), deep anterior lamellar keratoplasty (DALK, n = 187, 16.3%), Descemet's stripping automated endothelial keratoplasty (n = 171, 14.9%), and keratolimbal allograft (n = 2, 0.1%) in descending order. In children (aged ≤18 years), the most common indication was keratoconus (n = 32, 41.6%), and the most common technique was PKP (n = 50, 64.9%). In patients aged 19-27 years, the most common indication was keratoconus (n = 89, 64.5%), and the most common technique was PKP (n = 75, 54.4%). CONCLUSION: Infectious corneal ulcer was the most common indication, and PKP was the most prevalent technique in patients undergoing corneal transplantation. DALK was an emerging alternative surgical treatment in patients with corneal disorders in which corneal endothelium is spared.
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spelling pubmed-65047242019-05-21 Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center Jamali, Hossein Gholampour, Ahmad Reza J Ophthalmic Vis Res Original Article PURPOSE: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. METHODS: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran from September, 2012 to September, 2017 were reviewed. RESULTS: A total of 1149 eyes of 956 patients underwent corneal transplantation. The most common indication was infectious corneal ulcers (n = 296, 25.8%), followed by keratoconus (n = 243, 21.1%), bullous keratopathy (n = 219, 19.1%), failed grafts (n = 117, 10.2%), non-herpetic corneal scars (n = 113, 9.8%), corneal stromal dystrophies (n = 33, 2.9%), pellucid marginal degeneration (n = 31, 2.7%), and trauma (n = 26, 2.3%); other indications included thin descemetocele, post-herpetic corneal scar, endothelial corneal dystrophies, anterior segment dysgenesis, corneal ectasia after laser in situ keratomileusis, and corneal fibrosis. Corneal transplantation techniques included penetrating keratoplasty (PKP, n = 789, 68.7%), deep anterior lamellar keratoplasty (DALK, n = 187, 16.3%), Descemet's stripping automated endothelial keratoplasty (n = 171, 14.9%), and keratolimbal allograft (n = 2, 0.1%) in descending order. In children (aged ≤18 years), the most common indication was keratoconus (n = 32, 41.6%), and the most common technique was PKP (n = 50, 64.9%). In patients aged 19-27 years, the most common indication was keratoconus (n = 89, 64.5%), and the most common technique was PKP (n = 75, 54.4%). CONCLUSION: Infectious corneal ulcer was the most common indication, and PKP was the most prevalent technique in patients undergoing corneal transplantation. DALK was an emerging alternative surgical treatment in patients with corneal disorders in which corneal endothelium is spared. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6504724/ /pubmed/31114647 http://dx.doi.org/10.4103/jovr.jovr_92_18 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jamali, Hossein
Gholampour, Ahmad Reza
Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title_full Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title_fullStr Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title_full_unstemmed Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title_short Indications and Surgical Techniques for Corneal Transplantation at a Tertiary Referral Center
title_sort indications and surgical techniques for corneal transplantation at a tertiary referral center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504724/
https://www.ncbi.nlm.nih.gov/pubmed/31114647
http://dx.doi.org/10.4103/jovr.jovr_92_18
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