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Synthesis and characterization of a new class of anti-angiogenic agents based on ruthenium clusters

New triruthenium-carbonyl clusters derivatized with glucose-modified bicyclophosphite ligands have been synthesized. These compounds were found to have cytostatic and cytotoxic activity and depending on the number of bicyclophosphite ligands, and could be tuned for either anti-cancer or specific ant...

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Detalles Bibliográficos
Autores principales: Nazarov, Alexey A., Baquié, Mathurin, Nowak-Sliwinska, Patrycja, Zava, Olivier, van Beijnum, Judy R., Groessl, Michael, Chisholm, Danielle M., Ahmadi, Zohrab, McIndoe, J. Scott, Griffioen, Arjan W., van den Bergh, Hubert, Dyson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504821/
https://www.ncbi.nlm.nih.gov/pubmed/23508096
http://dx.doi.org/10.1038/srep01485