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Extracellular Monomeric Tau Is Internalized by Astrocytes

Tau is a microtubule-associated protein that is expressed in neurons. However, in a group of neurodegenerative diseases named tauopathies – characterized by an increase in aggregated and/or hyperphosphorylated Tau – the protein accumulates inside other cells, such as astrocytes and microglia. Given...

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Detalles Bibliográficos
Autores principales: Perea, Juan Ramón, López, Esther, Díez-Ballesteros, José Carlos, Ávila, Jesús, Hernández, Félix, Bolós, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504834/
https://www.ncbi.nlm.nih.gov/pubmed/31118883
http://dx.doi.org/10.3389/fnins.2019.00442