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Active RNA polymerase II curbs chromatin movement

Chromosomes are not very mobile during interphase. In this issue, Nagashima et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201811090) propose that the overall stabilization of genome structure is achieved by loose connections between DNA regions brought about by transcriptionally active RNA...

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Detalles Bibliográficos
Autores principales: Hochberg-Laufer, Hodaya, Shav-Tal, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504891/
https://www.ncbi.nlm.nih.gov/pubmed/30948424
http://dx.doi.org/10.1083/jcb.201903050