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Extramitochondrial cardiolipin suggests a novel function of mitochondria in spermatogenesis

Mitochondria contain cardiolipin (CL), an organelle-specific phospholipid that carries four fatty acids with a strong preference for unsaturated chains. Unsaturation is essential for the stability and for the function of mitochondrial CL. Surprisingly, we found tetrapalmitoyl-CL (TPCL), a fully satu...

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Detalles Bibliográficos
Autores principales: Ren, Mindong, Xu, Yang, Erdjument-Bromage, Hediye, Donelian, Alec, Phoon, Colin K.L., Terada, Naohiro, Strathdee, Douglas, Neubert, Thomas A., Schlame, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504895/
https://www.ncbi.nlm.nih.gov/pubmed/30914420
http://dx.doi.org/10.1083/jcb.201808131