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Homeostatic scaling of active zone scaffolds maintains global synaptic strength

Synaptic terminals grow and retract throughout life, yet synaptic strength is maintained within stable physiological ranges. To study this process, we investigated Drosophila endophilin (endo) mutants. Although active zone (AZ) number is doubled in endo mutants, a compensatory reduction in their siz...

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Detalles Bibliográficos
Autores principales: Goel, Pragya, Dufour Bergeron, Dominique, Böhme, Mathias A., Nunnelly, Luke, Lehmann, Martin, Buser, Christopher, Walter, Alexander M., Sigrist, Stephan J., Dickman, Dion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504899/
https://www.ncbi.nlm.nih.gov/pubmed/30914419
http://dx.doi.org/10.1083/jcb.201807165