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GPCR-independent activation of G proteins promotes apical cell constriction in vivo

Heterotrimeric G proteins are signaling switches that control organismal morphogenesis across metazoans. In invertebrates, specific GPCRs instruct G proteins to promote collective apical cell constriction in the context of epithelial tissue morphogenesis. In contrast, tissue-specific factors that in...

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Detalles Bibliográficos
Autores principales: Marivin, Arthur, Morozova, Veronika, Walawalkar, Isha, Leyme, Anthony, Kretov, Dmitry A., Cifuentes, Daniel, Dominguez, Isabel, Garcia-Marcos, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504902/
https://www.ncbi.nlm.nih.gov/pubmed/30948426
http://dx.doi.org/10.1083/jcb.201811174