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Pirfenidone prevents acute kidney injury in the rat

BACKGROUND: Pirfenidone is an orally active drug used for the treatment of idiopathic pulmonary fibrosis to slow loss of lung function; it acts mainly through an antifibrotic effect but also possesses antioxidant and anti-inflammatory properties. We assessed the effect of prophylactic administration...

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Detalles Bibliográficos
Autores principales: Lima-Posada, Ixchel, Fontana, Francesco, Pérez-Villalva, Rosalba, Berman-Parks, Nathan, Bobadilla, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505112/
https://www.ncbi.nlm.nih.gov/pubmed/31068174
http://dx.doi.org/10.1186/s12882-019-1364-4