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Imperfect Linkage Disequilibrium Generates Phantom Epistasis (& Perils of Big Data)
The genetic architecture of complex human traits and diseases is affected by large number of possibly interacting genes, but detecting epistatic interactions can be challenging. In the last decade, several studies have alluded to problems that linkage disequilibrium can create when testing for epist...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505142/ https://www.ncbi.nlm.nih.gov/pubmed/30877081 http://dx.doi.org/10.1534/g3.119.400101 |