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In vitro characterization of odorranalectin for peptide-based drug delivery across the blood–brain barrier

BACKGROUND: The use of siRNA-based gene silencing has been recently underscored as a potential therapeutic strategy for the treatment of neurological disorders. However, the stability of siRNA and other small molecule therapeutics is challenged by their intrinsic instability and limited passage acro...

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Detalles Bibliográficos
Autores principales: Sajja, Ravi K., Cudic, Predrag, Cucullo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505199/
https://www.ncbi.nlm.nih.gov/pubmed/31068126
http://dx.doi.org/10.1186/s12868-019-0504-x