In silico modeling of phosphorylation dependent and independent c-Myc degradation

BACKGROUND: c-Myc plays an important role in cell proliferation, cell growth and in differentiation, making it a key regulator for carcinogenesis and pluripotency. Tight control of c-myc turnover is required by ubiquitin-mediated degradation. This is achieved in the system by two F-box proteins Skp2...

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Detalles Bibliográficos
Autores principales: Chakravorty, Debangana, Banerjee, Krishnendu, Mapder, Tarunendu, Saha, Sudipto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505206/
https://www.ncbi.nlm.nih.gov/pubmed/31068129
http://dx.doi.org/10.1186/s12859-019-2846-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505206/
https://www.ncbi.nlm.nih.gov/pubmed/31068129
http://dx.doi.org/10.1186/s12859-019-2846-x

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