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Treatment of gonadotropin deficiency during the first year of life: long-term observation and outcome in five boys

STUDY QUESTION: What is the peripubertal outcome of recombinant human FSH (r-hFSH) treatment during minipuberty in boys with congenital hypogonadotropic hypogonadism (CHH)? SUMMARY ANSWER: Sertoli-cell response to r-hFSH, given during the minipuberty of infancy, appears insufficient to maintain Sert...

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Detalles Bibliográficos
Autores principales: Kohva, Ella, Huopio, Hanna, Hietamäki, Johanna, Hero, Matti, Miettinen, Päivi J, Raivio, Taneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505442/
https://www.ncbi.nlm.nih.gov/pubmed/31067328
http://dx.doi.org/10.1093/humrep/dez040