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A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal

Pancreatic cancer is one of the most lethal common cancers. The cell of origin of pancreatic ductal adenocarcinoma (PDAC) has been controversial, and recent evidence suggested acinar cells as the most probable candidate. However, the genetic alterations driving the transformation of pancreatic acina...

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Detalles Bibliográficos
Autores principales: Tu, Qiu, Yang, Dong, Zhang, Xianning, Jia, Xintong, An, Sanqi, Yan, Lanzhen, Dai, Hongjuan, Ma, Yuhua, Tang, Chengwei, Tong, Weimin, Hou, Zongliu, Lv, Longbao, Tan, Jing, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505477/
https://www.ncbi.nlm.nih.gov/pubmed/30910991
http://dx.doi.org/10.1242/dmm.038703