Cobalt Administration Causes Reduced Contractility with Parallel Increases in TRPC6 and TRPM7 Transporter Protein Expression in Adult Rat Hearts

Exposure to circulating cobalt (Co(2+)) in patients with metal-on-metal orthopaedic hip implants has been linked to cardiotoxicity but the underlying mechanism(s) remain undefined. The aim of the current study was to examine the effects of Co(2+) on the heart in vivo and specifically on cardiac fibr...

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Detalles Bibliográficos
Autores principales: Laovitthayanggoon, Sarunya, Henderson, Catherine J., McCluskey, Claire, MacDonald, Margaret, Tate, Rothwelle J., Grant, M. Helen, Currie, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505488/
https://www.ncbi.nlm.nih.gov/pubmed/30523498
http://dx.doi.org/10.1007/s12012-018-9498-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505488/
https://www.ncbi.nlm.nih.gov/pubmed/30523498
http://dx.doi.org/10.1007/s12012-018-9498-3

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