Bezafibrate Upregulates Mitochondrial Biogenesis and Influence Neural Differentiation of Human-Induced Pluripotent Stem Cells

Bezafibrate (BZ) regulates mitochondrial biogenesis by activation of PPAR’s receptors and enhancing the level of PGC-1α coactivator. In this report, we investigated the effect of BZ on the expression of genes (1) that are linked to different pathways involved in mitochondrial biogenesis, e.g., regul...

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Detalles Bibliográficos
Autores principales: Augustyniak, Justyna, Lenart, Jacek, Gaj, Paweł, Kolanowska, Monika, Jazdzewski, Krystian, Stepien, Piotr Pawel, Buzanska, Leonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505510/
https://www.ncbi.nlm.nih.gov/pubmed/30315479
http://dx.doi.org/10.1007/s12035-018-1368-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505510/
https://www.ncbi.nlm.nih.gov/pubmed/30315479
http://dx.doi.org/10.1007/s12035-018-1368-2

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