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Choline Rescues Behavioural Deficits in a Mouse Model of Rett Syndrome by Modulating Neuronal Plasticity

Rett syndrome (RTT) is a postnatal neurodevelopmental disorder that primarily affects girls, with 95% of RTT cases resulting from mutations in the methyl-CpG-binding protein 2 (MECP2) gene. Choline, a dietary micronutrient found in most foods, has been shown to be important for brain development and...

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Detalles Bibliográficos
Autores principales: Chin, Eunice W. M., Lim, Wee Meng, Ma, Dongliang, Rosales, Francisco J., Goh, Eyleen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505515/
https://www.ncbi.nlm.nih.gov/pubmed/30220058
http://dx.doi.org/10.1007/s12035-018-1345-9