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Topography of Simulated Intestinal Equilibrium Solubility

[Image: see text] Oral administration of a solid dosage form requires drug dissolution in the gastrointestinal tract before absorption. Solubility is a key factor controlling dissolution, and it is recognized that, within the intestinal tract, this is influenced by the luminal fluid pH, amphiphile c...

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Detalles Bibliográficos
Autores principales: Dunn, Claire, Perrier, Jeremy, Khadra, Ibrahim, Wilson, Clive G., Halbert, Gavin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505523/
https://www.ncbi.nlm.nih.gov/pubmed/30848917
http://dx.doi.org/10.1021/acs.molpharmaceut.8b01238