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Topography of Simulated Intestinal Equilibrium Solubility
[Image: see text] Oral administration of a solid dosage form requires drug dissolution in the gastrointestinal tract before absorption. Solubility is a key factor controlling dissolution, and it is recognized that, within the intestinal tract, this is influenced by the luminal fluid pH, amphiphile c...
Autores principales: | Dunn, Claire, Perrier, Jeremy, Khadra, Ibrahim, Wilson, Clive G., Halbert, Gavin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505523/ https://www.ncbi.nlm.nih.gov/pubmed/30848917 http://dx.doi.org/10.1021/acs.molpharmaceut.8b01238 |
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