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Computational analysis of data from a genome-wide screening identifies new PARP1 functional interactors as potential therapeutic targets

Knowledge of interaction network between different proteins can be a useful tool in cancer therapy. To develop new therapeutic treatments, understanding how these proteins contribute to dysregulated cellular pathways is an important task. PARP1 inhibitors are drugs used in cancer therapy, in particu...

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Detalles Bibliográficos
Autores principales: Lodovichi, Samuele, Mercatanti, Alberto, Cervelli, Tiziana, Galli, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505629/
https://www.ncbi.nlm.nih.gov/pubmed/31105872
http://dx.doi.org/10.18632/oncotarget.26812