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Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts

Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission. Thus, identification of new therapeutic agents that simultaneously suppress MM growth and protect bone is an unmet need. Herein, we examined the e...

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Detalles Bibliográficos
Autores principales: Delgado-Calle, Jesus, Kurihara, Noriyoshi, Atkinson, Emily G., Nelson, Jessica, Miyagawa, Kazuaki, Galmarini, Carlos Maria, Roodman, G. David, Bellido, Teresita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505631/
https://www.ncbi.nlm.nih.gov/pubmed/31105871
http://dx.doi.org/10.18632/oncotarget.26831