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Live pigs produced from genome edited zygotes

Transcription activator-like effector nuclease (TALEN) and zinc finger nuclease (ZFN) genome editing technology enables site directed engineering of the genome. Here we demonstrate for the first time that both TALEN and ZFN injected directly into pig zygotes can produce live genome edited pigs. Mono...

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Detalles Bibliográficos
Autores principales: Lillico, Simon G., Proudfoot, Chris, Carlson, Daniel F., Stverakova, Dana, Neil, Claire, Blain, Carol, King, Tim J., Ritchie, William A., Tan, Wenfang, Mileham, Alan J., McLaren, David G., Fahrenkrug, Scott C., Whitelaw, C. Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505673/
https://www.ncbi.nlm.nih.gov/pubmed/24108318
http://dx.doi.org/10.1038/srep02847