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Requirement for YAP1 signaling in myxoid liposarcoma

Myxoid liposarcomas (MLS), malignant tumors of adipocyte origin, are driven by the FUS‐DDIT3 fusion gene encoding an aberrant transcription factor. The mechanisms whereby FUS‐DDIT3 mediates sarcomagenesis are incompletely understood, and strategies to selectively target MLS cells remain elusive. Her...

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Detalles Bibliográficos
Autores principales: Trautmann, Marcel, Cheng, Ya‐Yun, Jensen, Patrizia, Azoitei, Ninel, Brunner, Ines, Hüllein, Jennifer, Slabicki, Mikolaj, Isfort, Ilka, Cyra, Magdalene, Berthold, Ruth, Wardelmann, Eva, Huss, Sebastian, Altvater, Bianca, Rossig, Claudia, Hafner, Susanne, Simmet, Thomas, Ståhlberg, Anders, Åman, Pierre, Zenz, Thorsten, Lange, Undine, Kindler, Thomas, Scholl, Claudia, Hartmann, Wolfgang, Fröhling, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505681/
https://www.ncbi.nlm.nih.gov/pubmed/30898787
http://dx.doi.org/10.15252/emmm.201809889