Efficacy of simultaneous VEGF‐A/ANG‐2 neutralization in suppressing spontaneous choroidal neovascularization

This study independently confirms in vivo in the JR5558 mouse model of aberrant retinal angiogenesis, that simultaneous VEGF‐A and ANG‐2 neutralization using a bispecific anti‐VEGF‐A/ANG‐2 antibody reduces vascular leakage, immune reactivity and apoptosis more effectively than either agent alone.[Im...

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Detalles Bibliográficos
Autores principales: Foxton, Richard H, Uhles, Sabine, Grüner, Sabine, Revelant, Franco, Ullmer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505683/
https://www.ncbi.nlm.nih.gov/pubmed/31040126
http://dx.doi.org/10.15252/emmm.201810204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505683/
https://www.ncbi.nlm.nih.gov/pubmed/31040126
http://dx.doi.org/10.15252/emmm.201810204

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