Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7

Nuclear and mitochondrial genome mutations lead to various mitochondrial diseases, many of which affect the mitochondrial respiratory chain. The proteome of the intermembrane space (IMS) of mitochondria consists of several important assembly factors that participate in the biogenesis of mitochondria...

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Detalles Bibliográficos
Autores principales: Mohanraj, Karthik, Wasilewski, Michal, Benincá, Cristiane, Cysewski, Dominik, Poznanski, Jaroslaw, Sakowska, Paulina, Bugajska, Zaneta, Deckers, Markus, Dennerlein, Sven, Fernandez‐Vizarra, Erika, Rehling, Peter, Dadlez, Michal, Zeviani, Massimo, Chacinska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505684/
https://www.ncbi.nlm.nih.gov/pubmed/30885959
http://dx.doi.org/10.15252/emmm.201809561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505684/
https://www.ncbi.nlm.nih.gov/pubmed/30885959
http://dx.doi.org/10.15252/emmm.201809561

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