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Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain

Neuropathic pain results from nerve injuries that cause ectopic firing and increased nociceptive signal transmission due to activation of key membrane receptors and channels. The dysregulation of trafficking of voltage-gated ion channels is an emerging mechanism in the etiology of neuropathic pain....

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Detalles Bibliográficos
Autores principales: Moutal, Aubin, Luo, Shizhen, Largent-Milnes, Tally M., Vanderah, Todd W., Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505708/
https://www.ncbi.nlm.nih.gov/pubmed/31080913
http://dx.doi.org/10.1016/j.ynpai.2018.07.003