Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning

Inherited erythromelalgia (IEM) is a chronic pain disorder caused by gain-of-function mutations of peripheral sodium channel Nav1.7, in which warmth triggers severe pain. Little is known about the brain representation of pain in IEM. Here we study two subjects with the IEM Nav1.7-S241T mutation usin...

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Detalles Bibliográficos
Autores principales: Geha, Paul, Schulman, Betsy R., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505710/
https://www.ncbi.nlm.nih.gov/pubmed/31080911
http://dx.doi.org/10.1016/j.ynpai.2018.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505710/
https://www.ncbi.nlm.nih.gov/pubmed/31080911
http://dx.doi.org/10.1016/j.ynpai.2018.01.002

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