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Brain activity associated with pain in inherited erythromelalgia: stimulus-free pain engages brain areas involved in valuation and learning
Inherited erythromelalgia (IEM) is a chronic pain disorder caused by gain-of-function mutations of peripheral sodium channel Nav1.7, in which warmth triggers severe pain. Little is known about the brain representation of pain in IEM. Here we study two subjects with the IEM Nav1.7-S241T mutation usin...
Autores principales: | Geha, Paul, Schulman, Betsy R., Dib-Hajj, Sulayman D., Waxman, Stephen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505710/ https://www.ncbi.nlm.nih.gov/pubmed/31080911 http://dx.doi.org/10.1016/j.ynpai.2018.01.002 |
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