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The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution

The visualisation and quantitative analysis of the native drug distribution in a pre-clinical or clinical setting are desirable for evaluating drug effects and optimising drug design. Here, using matrix-assisted laser desorption ionisation imaging mass spectrometry (MALDI-IMS) with enhanced resoluti...

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Detalles Bibliográficos
Autores principales: Yasunaga, Masahiro, Furuta, Masaru, Ogata, Koretsugu, Koga, Yoshikatsu, Yamamoto, Yoshiyuki, Takigahira, Misato, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505718/
https://www.ncbi.nlm.nih.gov/pubmed/24157937
http://dx.doi.org/10.1038/srep03050