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The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution
The visualisation and quantitative analysis of the native drug distribution in a pre-clinical or clinical setting are desirable for evaluating drug effects and optimising drug design. Here, using matrix-assisted laser desorption ionisation imaging mass spectrometry (MALDI-IMS) with enhanced resoluti...
Autores principales: | Yasunaga, Masahiro, Furuta, Masaru, Ogata, Koretsugu, Koga, Yoshikatsu, Yamamoto, Yoshiyuki, Takigahira, Misato, Matsumura, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505718/ https://www.ncbi.nlm.nih.gov/pubmed/24157937 http://dx.doi.org/10.1038/srep03050 |
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