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Distinct roles for MDA5 and TLR3 in the acute response to inhaled double-stranded RNA

The airway epithelial barrier is critical for preventing pathogen invasion and translocation of inhaled particles into the lung. Epithelial cells also serve an important sentinel role after infection and release various pro-inflammatory mediators that recruit and activate immune cells. Airway epithe...

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Detalles Bibliográficos
Autores principales: Veazey, Janelle M., Chapman, Timothy J., Smyth, Timothy R., Hillman, Sara E., Eliseeva, Sophia I., Georas, Steve N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505938/
https://www.ncbi.nlm.nih.gov/pubmed/31067281
http://dx.doi.org/10.1371/journal.pone.0216056