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Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation

Clonal hematopoiesis of indeterminate potential (CHIP) is a recently identified process where older patients accumulate distinct subclones defined by recurring somatic mutations in hematopoietic stem cells. CHIP’s implications for stem cell transplantation have been harder to identify due to the hig...

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Detalles Bibliográficos
Autores principales: Park, Derek S., Akuffo, Afua A., Muench, David E., Grimes, H. Leighton, Epling-Burnette, Pearlie K., Maini, Philip K., Anderson, Alexander R. A., Bonsall, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505959/
https://www.ncbi.nlm.nih.gov/pubmed/31026273
http://dx.doi.org/10.1371/journal.pcbi.1006913