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Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation
Clonal hematopoiesis of indeterminate potential (CHIP) is a recently identified process where older patients accumulate distinct subclones defined by recurring somatic mutations in hematopoietic stem cells. CHIP’s implications for stem cell transplantation have been harder to identify due to the hig...
Autores principales: | Park, Derek S., Akuffo, Afua A., Muench, David E., Grimes, H. Leighton, Epling-Burnette, Pearlie K., Maini, Philip K., Anderson, Alexander R. A., Bonsall, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505959/ https://www.ncbi.nlm.nih.gov/pubmed/31026273 http://dx.doi.org/10.1371/journal.pcbi.1006913 |
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