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Study protocol for a randomised controlled trial of carvedilol versus variceal band ligation in primary prevention of variceal bleeding in liver cirrhosis (CALIBRE trial)

INTRODUCTION: Liver cirrhosis is the fifth largest cause of adult deaths, and a major complication, variceal bleeding is associated with a 1-year mortality of 40%. There is uncertainty on the first-line therapy for prevention of variceal bleeding owing to a lack of adequately powered trials comparin...

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Detalles Bibliográficos
Autores principales: Tripathi, Dhiraj, Hayes, Peter Clive, Richardson, Paul, Rowe, Ian, Ferguson, James, Devine, Peter, Mathers, Jonathan, Poyner, Christopher, Jowett, Sue, Handley, Kelly, Grant, Margaret, Slinn, Gemma, Ahmed, Khaled, Brocklehurst, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506059/
https://www.ncbi.nlm.nih.gov/pubmed/31139428
http://dx.doi.org/10.1136/bmjgast-2019-000290