Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network

Drosophila provides an inexpensive and quantitative platform for measuring whole animal drug response. A complementary approach is virtual screening, where chemical libraries can be efficiently screened against protein target(s). Here, we present a unique discovery platform integrating structure-bas...

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Detalles Bibliográficos
Autores principales: Ung, Peter M. U., Sonoshita, Masahiro, Scopton, Alex P., Dar, Arvin C., Cagan, Ross L., Schlessinger, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506148/
https://www.ncbi.nlm.nih.gov/pubmed/31026276
http://dx.doi.org/10.1371/journal.pcbi.1006878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506148/
https://www.ncbi.nlm.nih.gov/pubmed/31026276
http://dx.doi.org/10.1371/journal.pcbi.1006878

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