Cargando…
Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
Drosophila provides an inexpensive and quantitative platform for measuring whole animal drug response. A complementary approach is virtual screening, where chemical libraries can be efficiently screened against protein target(s). Here, we present a unique discovery platform integrating structure-bas...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506148/ https://www.ncbi.nlm.nih.gov/pubmed/31026276 http://dx.doi.org/10.1371/journal.pcbi.1006878 |