AMPK activation regulates P-body dynamics in mouse sensory neurons in vitro and in vivo

Increased mRNA translation in sensory neurons following peripheral nerve injury contributes to the induction and maintenance of chronic neuropathic pain. Metformin, a common anti-diabetic drug and an activator of AMP-activated protein kinase (AMPK), inhibits cap-dependent mRNA translation and revers...

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Detalles Bibliográficos
Autores principales: Paige, Candler, Mejia, Galo, Dussor, Gregory, Price, Theodore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506165/
https://www.ncbi.nlm.nih.gov/pubmed/31080914
http://dx.doi.org/10.1016/j.ynpai.2018.100026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506165/
https://www.ncbi.nlm.nih.gov/pubmed/31080914
http://dx.doi.org/10.1016/j.ynpai.2018.100026

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