Analysis and minimization of cellular RNA editing by DNA adenine base editors

Adenine base editors (ABEs) enable precise and efficient conversion of target A•T base pairs to G•C base pairs in genomic DNA with a minimum of by-products. While ABEs have been reported to exhibit minimal off-target DNA editing, off-target editing of cellular RNA by ABEs has not been examined in de...

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Detalles Bibliográficos
Autores principales: Rees, Holly A., Wilson, Christopher, Doman, Jordan L., Liu, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506237/
https://www.ncbi.nlm.nih.gov/pubmed/31086823
http://dx.doi.org/10.1126/sciadv.aax5717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506237/
https://www.ncbi.nlm.nih.gov/pubmed/31086823
http://dx.doi.org/10.1126/sciadv.aax5717

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