USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

Resistance to platinum-based chemotherapy is a common event in patients with cancer, generally associated with tumor dissemination and metastasis. Whether platinum treatment per se activates molecular pathways linked to tumor spreading is not known. Here, we report that the ubiquitin-specific protea...

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Detalles Bibliográficos
Autores principales: Sonego, Maura, Pellarin, Ilenia, Costa, Alice, Vinciguerra, Gian Luca Rampioni, Coan, Michela, Kraut, Alexandra, D’Andrea, Sara, Dall’Acqua, Alessandra, Castillo-Tong, Dan Cacsire, Califano, Daniela, Losito, Simona, Spizzo, Riccardo, Couté, Yohann, Vecchione, Andrea, Belletti, Barbara, Schiappacassi, Monica, Baldassarre, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506239/
https://www.ncbi.nlm.nih.gov/pubmed/31086816
http://dx.doi.org/10.1126/sciadv.aav3235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506239/
https://www.ncbi.nlm.nih.gov/pubmed/31086816
http://dx.doi.org/10.1126/sciadv.aav3235

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