The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation

Pathological cardiac hypertrophy eventually leads to heart failure without adequate treatment. The immunoproteasome is an inducible form of the proteasome that is intimately involved in inflammatory diseases. Here, we found that the expression and activity of immunoproteasome catalytic subunit β5i w...

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Detalles Bibliográficos
Autores principales: Xie, Xin, Bi, Hai-Lian, Lai, Song, Zhang, Yun-Long, Li, Nan, Cao, Hua-Jun, Han, Ling, Wang, Hong-Xia, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506244/
https://www.ncbi.nlm.nih.gov/pubmed/31086810
http://dx.doi.org/10.1126/sciadv.aau0495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506244/
https://www.ncbi.nlm.nih.gov/pubmed/31086810
http://dx.doi.org/10.1126/sciadv.aau0495

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