SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres

Alternative lengthening of telomeres, or ALT, is a recombination-based process that maintains telomeres to render some cancer cells immortal. The prevailing view is that ALT is inhibited by heterochromatin because heterochromatin prevents recombination. To test this model, we used telomere-specific...

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Detalles Bibliográficos
Autores principales: Gauchier, Mathilde, Kan, Sophie, Barral, Amandine, Sauzet, Sandrine, Agirre, Eneritz, Bonnell, Erin, Saksouk, Nehmé, Barth, Teresa K., Ide, Satoru, Urbach, Serge, Wellinger, Raymund J., Luco, Reini F., Imhof, Axel, Déjardin, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506250/
https://www.ncbi.nlm.nih.gov/pubmed/31086817
http://dx.doi.org/10.1126/sciadv.aav3673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506250/
https://www.ncbi.nlm.nih.gov/pubmed/31086817
http://dx.doi.org/10.1126/sciadv.aav3673

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